L-selectin: Role in regulating homeostasis and cutaneous inflammation
نویسندگان
چکیده
منابع مشابه
L-selectin in inflammation, infection and immunity
L-selectin in inflammation, infection and immunity Nikolai A. Raffler, Jesús Rivera-Nieves, Klaus Ley* Department of Biomedical Engineering, University of Virginia Health System, Charlottesville, VA 22908-1394, USA Digestive Health Center of Excellence, University of Virginia Health System, Charlottesville, VA 22908-1394, USA Robert M. Berne Cardiovascular Research Center, University of Virgini...
متن کاملThe cytoplasmic domain of L-selectin participates in regulating L-selectin endoproteolysis.
Neutrophil recruitment at sites of inflammation is regulated by a series of adhesion and activation events. L-selectin (CD62L) is a leukocyte expressed adhesion protein that is important for neutrophil accumulation and rolling along the vascular endothelium. L-selectin is unique from other adhesion molecules involved in leukocyte transmigration in that its adhesiveness appears to be regulated p...
متن کاملThe role of inflammation in cutaneous repair
Inflammation is a fundamental component of the normal adult wound healing response occurring even in the absence of infection. It performs many beneficial roles such as the clearing of damaged cells and extracellular matrix (ECM), the removal of pathogens that might otherwise multiply and spread, and the secretion of mediators that regulate other aspects of wound healing such as proliferation, ...
متن کاملP-selectin deficiency exacerbates experimental glomerulonephritis: a protective role for endothelial P-selectin in inflammation.
P-selectin is a leukocyte adhesion receptor present in endothelial cells and platelets. We examined the role of P-selectin in the autologous phase of an accelerated model of anti-glomerular basement membrane (GBM) glomerulonephritis using P-selectin-deficient mice and chimeric mice expressing P-selectin only in platelets or endothelial cells. P-selectin-deficient mice exhibited more severe glom...
متن کاملThe role of peptide YY in regulating glucose homeostasis.
The gut-derived hormone peptide YY (PYY) is most commonly known for its effect on satiety, decreasing food intake and body weight in animals and humans. However, PYY is also involved in a wide range of digestive functions including regulating insulin secretion and glucose homeostasis. Over the last few years, there have been several interesting clinical and animal studies investigating the role...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Dermatological Science
سال: 2009
ISSN: 0923-1811
DOI: 10.1016/j.jdermsci.2009.10.001